Safety and effectiveness in children have not been established.ĭo not take this medicine if you have or have had any of the following: The active ingredient in ENDONE passes into breast milk and there is a possibility that your baby may be affected.ĭo not give this medicine to children. It may affect your developing baby if you take it during pregnancy.ĭo not breast-feed if you are taking this medicine. swelling of the face, lips, tongue or other parts of the bodyĭo not take this medicine if you are pregnant.Some of the symptoms of an allergic reaction may include: any of the ingredients listed at the end of this leaflet.any other narcotic analgesics such as morphine, codeine, or opium.any medicine containing oxycodone hydrochloride.Before you take ENDONE When you must not take itĭo not take ENDONE if you have an allergy to: watery eyes, runny nose, chills or yawningĮNDONE given to the mother during labour can cause breathing problems and signs of withdrawal in the newborn.increased heart rate, breathing rate or pupil size.loss of appetite, nausea, vomiting or diarrhoea.nervousness, restlessness, agitation, trouble sleeping or anxiety.If you stop taking this medicine suddenly, your pain may worsen and you may experience some or all of the following withdrawal symptoms: Speak to your doctor if this occurs.Ĭontinue taking your medicine for as long as your doctor tells you. If this happens, more may be needed to maintain the same effect. Tolerance to ENDONE may develop, which means that the effect of the medicine may decrease. Physical dependence means that you may experience withdrawal symptoms if you stop taking ENDONE suddenly, so it is important to take it exactly as directed by your doctor. Taking it may result in physical dependence. If abused it may become less able to reduce pain.Īs with all other opioid containing products, your body may become used to you taking ENDONE.
ENDONE may become habit forming causing mental and physical dependence. You can become addicted to ENDONE even if you take it exactly as prescribed. This medicine is only available with a doctor’s prescription. Your doctor may have prescribed it for another reason. This binding action changes your body’s perception of pain throughout the central nervous system producing the pain relieving (analgesic) effect.Īsk your doctor if you have any questions about why this medicine has been prescribed for you. The active ingredient in this medicine works by binding to receptors called opioid receptors, which are in your central nervous system. This medicine belongs to a group of medicines called narcotic analgesics. This medicine is used for the short-term management of severe pain. If you have any concerns about taking this medicine, ask your doctor or pharmacist. Your doctor has weighed the risks of you taking ENDONE against the benefits they expect it will have for you. It does not take the place of talking to your doctor or pharmacist.Īll medicines have risks and benefits. It does not contain all the available information. This leaflet answers some common questions about ENDONE. You must not drink alcohol while using ENDONE. Your doctor will minimise the dose and duration of use and monitor you for signs and symptoms of breathing difficulties and sedation. gabapentin and pregabalin), cannabis and alcohol may result in severe drowsiness, decreased awareness, breathing problems, coma and death. benzodiazepines), other pain relievers, antihistamines, antidepressants, antipsychotics, gabapentinoids (e.g. Using ENDONE with other medicines that can make you feel drowsy such as sleeping tablets (e.g. Use of other medicines while using ENDONE Your doctor will monitor you and change the dose as appropriate. These problems can occur at any time during use, but the risk is higher when first starting ENDONE and after a dose increase, if you are older or have an existing problem with your lungs. Your doctor will monitor you regularly during treatment.ĮNDONE can cause life-threatening or fatal breathing problems (slow, shallow, unusual or no breathing), even when used as recommended. ENDONE should only be used when your doctor decides that other treatment options are not able to effectively manage your pain or you cannot tolerate them.ĮNDONE poses risks of abuse, misuse and addiction which can lead to overdose and death.
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